The smart Trick of ceesdekker.net That Nobody is Discussing
The smart Trick of ceesdekker.net That Nobody is Discussing
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Nanotechnology offers a range of options to lead to biology. Below I'll existing illustrations where by nanofabrication – a chance to make confined buildings with Proportions at will – is used to look at the biophysics of single molecules and cells. I will present some illustrations from our lab:
Human Rad51 filaments on double- and solitary-stranded DNA: correlating regular and irregular kinds with recombination functionality.
Back in 1991, Sumio Iijima of your NEC Company had described the synthesis of carbon nanotubes. Band construction calculations proposed that these nanotubes could exhibit metallic band conduction. This may be a major advantage about the conducting polymers we had explored, which were being, the truth is, disordered semiconductors providing just variable-variety hopping conductivity.
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
2012, discovery that nucleoid occlusion underlies the precision of bacterial mobile division; and initial at any time analyze in the dynamics DNA supercoils and the invention of supercoil hopping
The coiled-coil of your human Rad50 DNA mend protein consists of unique segments of enhanced flexibility
We use nanofabricated microfluidic constructions to pattern spatial boundaries for germs and biomimetic vesicles with reconstituted protein networks https://www.ceesdekker.net and this assess the elemental purpose of spatial confinement for the molecular and mobile degree. Our assignments contain the following:
Studying DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.
‘You shouldn't just contemplate the issues of tomorrow, but will also evaluate the thoughts of your working day immediately after tomorrow’
Dekker began his investigate on solitary carbon nanotubes in 1993 when he setup a completely new line of investigation to study electrical transportation by means of one organic and natural molecules in between nanoelectrodes. In 1996 a breakthrough was understood with carbon nanotubes. This was reached in a collaboration Along with the group of Nobel laureate Richard Smalley. STM and nanolithography procedures have been utilized to exhibit that these nanotubes are quantum wires at The one-molecule degree, with outstanding Bodily Attributes.
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2001, discovery of solitary-electron transistors at area temperature depending on nanotubes; realization of very first logic circuits with carbon nanotube devices; and discovery of the molecular composition of DNA mend enzymes with AFM
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of an individual wire bridging two electrodes
‘I am driven by wonder and concerns. On a material level I find answers in physics, but I experience my deepest happiness with God. That religion also drives my science And exactly how I contend with people today.